When Seth Brundle makes a huge scientific and technological breakthrough in teleportation, he decides to test it on himself. Unbeknownst to him, a common housefly manages to get inside the device and the two become one.
Martin Brundle, born of the human/fly, is adopted by his father's place of employment (Bartok Inc.) while the employees simply wait for his mutant chromosomes to come out of their dormant state.
Industrialist François Delambre is called late at night by his sister-in-law, Helene Delambre, who tells him that she has just killed her husband, André. Reluctant at first, she eventually explains to the police that André invented a matter transportation apparatus and, while experimenting on...
A series of ghastly murders are being committed. The one similarity in each of the murders is that a strange buzzing sound is always heard right before the murder occurs. Is the killer invisible or possibly some other incredible creature?
Fifteen years after his father's experiments with matter transmission fail, Philippe Delambre and his uncle François attempt to create a matter transmission device on their own. However, their experiments have disastrous results, turning Philippe into a horrible half-man, half-fly creature.