A tribute to the high concept trashiness of B-movies, the film centres on a scientist who is trying to locate the gene that controls guilt, but transforms into a combination vampire and drag queen after being bitten by one of his lab rats.
A bright-eyed and idealistic young writer named Johnny Daze comes to town prowling for something to write about. What he finds is a sinister back alley forbidden zone peopled by gays, artists, prostitutes, transvestites and virtually every kind of conceivable bad influence.