It's 1986 and a group of grad students are close to discovering what happens to the human brain after staying awake for 200 hours, but something goes terribly wrong with a test subject. After their department is shut down, the team moves forward in secret - only this time on themselves.
JR, an aspiring news-anchor, forces her younger brother Colin to embark on a road trip to move her belongings out of her professor-turned-lover’s place. Traveling through New England, they uncomfortably run into old school-mates or revisit familial history from which they have long since diverged.
