The government sets up a zombie squad after an epidemic has made the world run rampant with living corpses. The team head off to Ohio to try and find a cure but soon run into a crazy cult of zombie lovers who are set on preserving the walking dead as they believe it's God's will.
Crawldaddy and her two kids are travelling across the country on the search for victims. The dysfunctional family has the disturbing habit of skinning people alive before killing them. When their van breaks down, they are put up by a friendly couple.
With the world gripped by a deadly pandemic, science denier Glenn Rollins turns to an experimental vaccine as treatment for a lingering sickness. Much to the surprise of his doctor, wife, and friends, the remedy immediately fixes what ails him. But Glenn will soon discover the only thing more fatal...
Convinced that a small independent film crew is actually a Satanic cult committing real-life atrocities, Officer John Dardin takes justice into his own hands-leading to a blood-soaked massacre where fiction and reality collide.