After drawing Betty Boop, Max Fleischer (live-action) leaves the studio; Betty and Koko try amateur dentistry, releasing enough laughing gas to convulse the 'real world.'
An animated interpretation of a rocket voyage to the moon demonstrates the scientific principles at play in theoretical space travel (such as gravity).
Big Chief Ugh-Amugh-Ugh is looking for a squaw. Meanwhile, Popeye and Olive are wrestling with their recalcitrant mule and Olive accidentally lands in the Indian camp. Popeye catches up to her. There's an unfair fight, and Popeye is about to be burned at the stake. He drops his spinach, but it...
Policeman Wimpy loses his handcuffed prisoner when he's distracted by a hamburger shop. The escapee drops into the weapon-filled pawnshop Popeye and Olive are running, and quickly gets in a fight with Popeye.
Wimpy is such a terrible helper that blacksmith Olive fires him. Both Popeye and Bluto see the help wanted sign; they compete for the position. Of course, their competition wrecks the shop.
Popeye, feeling sorry for the puppies in the window of Olive Oyl's pet shop, buys all the animals (mostly dogs) and sets them free. A parrot declines to go, singing the title song to explain why it likes it just fine in the shop. Meanwhile, the freed dogs are not faring well.
Popeye comes to ask Olive out, but finds she's gone off with the title character. Popeye goes to the circus (ringmaster Wimpy) looking for her, to find she's part of the act; an aerial battle ensues.
In a return to the Out of the Inkwell format, Betty Boop invents a pep formula to speed up lazy Pudgy, but it escapes into the real world with rapid results.