Ten years after the first American Pie movie, three new hapless virgins discover the Bible hidden in the school library at East Great Falls High. Unfortunately for them, the book is ruined, and with incomplete advice, the Bible leads them on a hilarious journey to lose their virginity.
When Jiajia, a young woman in Beijing who lives a luxurious life provided by her wealthy boyfriend, gets pregnant, she goes to the United States, hoping that the baby will be born an American citizen. There she meets Frank who offers help and makes her think twice about who her Mr. Right really is.
When a group of psychiatric hospital nurses invoke the spirit of Bloody Mary -- a supposed urban myth -- the slaughter begins. The legend is real, her vengeance is fatal, and to free her, all you have to do is say her name.