A scientist, Dr Hollander, takes his niece Miranda to Mexico in an attempt to reverse the effects of the alien DNA he used to create her. However the treatment goes horribly wrong, and sets Miranda on a killing spree as she sets out to find a mate.
They are not wild and crazy anymore, or at least they think so. Now, thanks to an offer nobody can't refuse, they will try to recapture that old rock and roll magic and give themselves a second chance.