Giuseppe Moscati, Doctor saint of Naples, was a doctor of the early twentieth century, from an aristocratic family devoted his career to serving the poor. The film focuses on the human side, partially leaving aside the spiritual part.
About the misadventures of Desiderio, a pretty young Neapolitan transsexual, and of her group of transvestite friends. Disappointed in love and politics, they set up an organic farm and psychological help centre for men in crisis.