Three convicted criminals escape from prison carrying only a güiro, a tambor and an accordion. During their journey, they meet with a bunch of interesting characters and are forced to use their musical skills to help them get home.
Ben, a frustrated writer, has decided to end his life. But when his suicide attempt is unknowingly interrupted by his neighbor, his life is thrown in disarray following a series of misadventures that will bring his world truly upside-down, giving him the reality check he needed.
Cristina, Belisario, and Benito become guardians of justice to combat neighborhood crime. Eventually, they confront an evil businessman who wants to gain political advantage using a dangerous virus.
An unemployed man, overwhelmed by problems, attempts to jump from a ninth floor. A crowd gathers in the street trying to convince him of not ending his life.
Pedro José falls in love with Natalia after meeting her in a gym. She is a teacher and coordinator of a summer camp, with her boyfriend Hector. Pedro José will try the impossible to enter the camp in the company of his friends and conquer Natalia's love.