A boy takes in a stray dog, later finding out that it's an ultra-intelligent runaway from a genetic research lab. Unbeknownst to him, the dog is being stalked by another escaped creature that's not quite so friendly.
Now an insurance adjuster, former C.I.A. agent John Pope becomes the target of both Mafia and C.I.A. hitmen. Pope is the last of the secret agents who can ruin a money laundering collaboration between a corrupt agency leader (Kirkpatrick) and a Mafia boss (Matera).